Overview of Aseptic Vacuum Drying Machine Equipment
The HPG sterile rake dryer is a multifunctional fully enclosed vacuum drying equipment that integrates drying and mixing, suitable for the production of sterile products in the pharmaceutical industry. Mainly used for antibiotics API、 Drying and mixing of powders with high hygiene requirements such as fine chemicals. In order to ensure complete isolation between the process area and the technical area, the HPG sterile rake dryer adopts a horizontal through wall installation method to fundamentally avoid contamination of the product.
The HPG type dryer from Changzhou Baide Drying is suitable for batch drying of the following types of products: granular crystalline products/heat sensitive products that can even denature at low temperatures/toxic or easily oxidizable products from filter presses or centrifuges. Due to the continuous mixing and stirring of the product, excellent heat transfer performance for heating and cooling the powder, online sampling, and no need to break the vacuum or shut down, this dryer greatly shortens the drying time.

Working principle of sterile vacuum dryer
Aseptic rake dryer is an economical and powerful multi-purpose equipment suitable for large-scale production. Suitable for use as a mixer, reactor, or dryer, it can be designed to operate under vacuum or pressure as required. By heating the tank wall, head, stirring shaft, and stirring blade, the heating area is very large, resulting in particularly good heat transfer efficiency. Shaft seals can use packing boxes or be interchangeable with double end wet, dry, or non-contact mechanical seals.
Due to the small gap between the stirring blade and the tank wall, as well as the special design of the stirring blade, the discharge performance is very good. Compliant with cGMP and FDAHDS vacuum rake dryers, suitable for the production of sterile products in the pharmaceutical industry, including: a quick opening flat head; A special cantilever mounted mixer with heated mixing blades installed on top; A dual end mechanical seal; A dust collector; A discharge valve installed at the bottom or a piston type discharge valve installed on the flat head.

Performance characteristics of sterile vacuum dryer
1. Good sealing performance and high cleanliness, all sealing components are made of materials that meet GMP requirements;
2. No foreign matter contamination: A special mechanical seal is used between the mixing shaft and the chamber to ensure that the product is free from contamination by lubricating oil and other foreign objects, meeting the requirements of sterile production;
3. High thermal efficiency: All surfaces in contact with the material are heated, such as the tank, rear head, front head, mixer, and dust collector, with uniform heat tracing and a large heat transfer area, which can provide efficient heat transfer efficiency;
4. Good drying effect: The heated stirring shaft effectively avoids material wall hanging and agglomeration while replacing the inner and outer layers of the material, which is beneficial for drying and provides the quality of the dried material;
5. Quick opening flat head is easy to open, clean and verify, with smooth discharge, sampling and unloading, and minimal residue;
6. Double end wet, dry, or non-contact mechanical seals are suitable for the production of sterile products;
7. Equipped with CIP cleaning and SIP in-situ high-temperature sterilization system, it can achieve processing conversion of different products in a short period of time;
8. Compliant with cGMP and FDA;

Technical parameter table of sterile vacuum dryer